Chewable tablets for dogs 7.5-15 kg Merial Frontline NexgarD Spectra No. 3 at mirkorma.ru

Composition of the drug

The tablets contain two substances in equal proportions:

Afoxolaner – kills skin parasites;
Milbemycin oxime is an anthelmintic component.

Unlike drops on the withers, tablets act from the inside. Saliva quickly breaks down the medicine, and the gastrointestinal mucosa promotes rapid absorption into the blood. Therefore, within an hour the components begin to affect the parasites. And a person can pet, bathe, or cut a pet without fear.

The advantages include meaty taste and soft consistency of the pills. Dogs eat them with pleasure, both with food and as a separate treat.

The drug is available in five versions depending on the dog’s weight.

2-4 kg;
4-10 kg;
10-25 kg;
25-50 kg;
50-60 kg.

Remember, the tablet must be given whole. Its breaking and crushing is unacceptable.

In veterinary pharmacies you can see a similar box on the counter with a two-word name: Frontline and Nexgard. This medicine contains only afoxolaner. It is prescribed for the prevention of bites by fleas and ixodid ticks. The drug has no effect on helminths.

NEXGARD SPECTRA

NexgarD Spectra is a combination antiparasitic drug.
The active components included in the drug - afoxolaner and milbemycin oxime - provide its wide spectrum of antiparasitic action against ectoparasites and nematodes that parasitize dogs: fleas (Ctenocephalides felis, Ctenocephalides can is); ixodid ticks (Dermacentor variabilis, Dermacentor reticulatus, Rhipicephalus sanguineus, Ixodes scapularis, Ixodes ricinus, Ixodes holocyclus, Haemaphysalis longicornis, Amblyomma americanum); gastrointestinal nematodes (Toxocara canis, Toxascaris leonina, Ancylostoma caninum, Ancylostoma braziliense, Trichuris vulpis); heartworm larvae (Dirofilaria immitis).

Afoxolaner is an insectoacaricide of the isoxazoline group; its mechanism of action is to block GABA-dependent arthropod receptors, hyperexcite neurons, disrupt the transmission of nerve impulses, which leads to paralysis and death of ectoparasites. After oral administration, afoxolaner is easily absorbed from the gastrointestinal tract and reaches the systemic circulation, the maximum concentration in plasma is observed 2-4 hours after administration, bioavailability is 88%. Afoxolaner is slowly metabolized to form hydroxylated compounds and is excreted from the body mainly in bile and slightly in urine. The half-life of afoxolaner is 14 days.

Milbemycin oxime is a macrocyclic lactone, active against the larvae and adults of nematodes parasitizing the gastrointestinal tract of dogs, as well as the larvae of Dirofilaria immitis. The mechanism of action of milbemycin is due to an increase in the permeability of cell membranes to chlorine ions (CH), which leads to overpolarization of the membranes of nerve and muscle tissue cells, paralysis and death of the parasite. The maximum concentration of milbemycin oxime in the blood plasma of dogs is achieved within 1-2 hours, bioavailability is 81%. The compound is excreted from the body mainly unchanged; the half-life is about 1.5 days.

The insecticidal effect of the drug begins 30 minutes after its oral administration, the death of fleas and ixodid ticks on the animal occurs within 6 hours and 24 hours, respectively. A single use of the drug prevents re-infection for 1 month; The death of fleas occurs before eggs are laid, which prevents contamination of premises with eggs and insect larvae.

In terms of the degree of impact on the body, NexgarD Spectra is a low-hazard substance (hazard class 4 according to GOST 12.1.007-76), in recommended doses it does not have teratogenic, embryotoxic, mutagenic properties, and does not have a local irritant effect. The drug is toxic to bees, as well as fish and other aquatic organisms.

Indications for use

Nexgard Spectra for dogs and puppies is prescribed if their body is attacked by the following parasites:

fleas;
ixodid ticks;
roundworms;
hookworms;
whipworms;
dirofilaria.

The components of the drug interfere with the transmission of nerve impulses. This effect kills skin parasites and paralyzes helminths. Afoxolaner is excreted from the body in bile and urine within 14 days. Milbemycin oxime is almost not absorbed into the digestive tract and is excreted along with feces, worms, and eggs.

NexgarD SPECTRA insectoacaricidal tablets for dogs from 7.5 to 15 kg 3 tablets

Action

Contraindications and side effects

Nexgard Spectra has a gentle effect. But it is intended to treat dogs weighing from 2 kg. Therefore, the drug should not be given to puppies of decorative breeds and dogs weighing less than this indicator. The medicine is also contraindicated for pets suffering from infectious and other complex diseases.

Side effects are most common in Sheltie, Bobtail, and Collie dogs. Moreover, if an allergic reaction occurs to both components, the symptoms will be more dangerous for the pet. These include:

increased body temperature;
increased salivation;
diarrhea and vomiting.

A drug overdose also occurs.

It is necessary to give the medicine with extreme caution to dogs that have had an allergic reaction to other antiparasitic drugs or problems with the immune system. Nexgard Spectra causes mild itching. Therefore, it is not prescribed to pets with open wounds, fresh scratches, or skin diseases.

The basis of any anthelmintic is a poison that destroys parasites. Therefore, the owner must observe safety precautions when working with the drug - you cannot smoke, eat or drink at this time. Next, you need to wash your hands with soap and dispose of any remaining packaging. If particles of the medicine accidentally come into contact with the mucous membrane, you should consult a doctor; you should bring instructions with you indicating the composition.

High-quality analogues

Nexgard Spectra has the greatest range of action, as it can simultaneously act on helminths and skin parasites. Most high-quality analogues solve only one problem. Thus, Bravecto chewable tablets destroy ticks and fleas within 7-12 hours. Regular preventive medication helps restore your pet's coat.

Another quality medicine for skin parasites is Comfortis. The tablets are made in the UK from waste products of soil microorganisms. They are safe for warm-blooded animals, but poisonous to ticks and insects.

The main component, spinosad, remains in the dog’s blood for up to two weeks, gradually destroying fleas developing from eggs.

Chewable tablets for dogs 7.5-15 kg Merial Frontline NexgarD Spectra No. 3

NexgarD Spectra 7.5-15 kg (M) tablets for fleas, worms and ticks, 3 tablets for oral use (chewable with beef flavor). NexGard Spectra is a combination of two active ingredients that are active against the most common external and internal parasites of dogs. New tasty chewable tablet for dogs is the next generation of Frontline Nexgard, aimed at protecting against fleas and ticks. NexgarD Spectra, in addition to its effect on external parasites, fights against helminths - roundworms, whipworms and hookworms, and is also aimed at protecting dogs from dirofilariasis.

Tablets based on soy protein with the taste and smell of beef are, in most cases, eaten with pleasure by dogs. Since the tablets are made on a plant basis, they do not cause allergies to animal proteins.

The active ingredients included in the drug (afoxolaner and milbemycin oxime) provide a wide range of antiparasitic effects against ectoparasites and helminths parasitizing dogs. The drug is active against adult fleas, ticks, gastrointestinal nematodes, heartworm larvae.

PHARMACOLOGICAL PROPERTIES

Combined antiparasitic drug. The drug contains active components - afoxolaner and milbemycin oxime, which provide a wide range of antiparasitic effects against ectoparasites and nematodes that parasitize dogs: fleas (Ctenocephalides felis, Ctenocephalides can is), ixodid ticks (Dermacentor variabilis, Dermacentor reticulatus, Rhipicephalus sanguineus, Ixodes scapularis, Ixodes ricinus, Ixodes holocyclus, Haemaphysalis longicornis, Amblyomma americanum), gastrointestinal nematodes (Toxocara canis, Toxascaris leonina, Ancylostoma caninum, Ancylostoma braziliense, Trichuris vulpis) and heartworm larvae (Dirofilaria immitis).

Afoxolaner is an insectoacaricide of the isoxazoline group. It blocks GABA-dependent receptors of arthropods, and also creates hyperexcitation of neurons, disruption of the transmission of nerve impulses, which leads to paralysis and death of parasites. Afoxolaner is easily absorbed from the gastrointestinal tract and reaches the systemic circulation, its maximum concentration in plasma is observed 2-4 hours after taking the tablet. It is excreted from the body mainly with bile and slightly with urine. The half-life of afoxolaner is 14 days.

Milbemycin oxime is a macrocyclic lactone that is active against helminths - larvae and adults of nematodes that parasitize the gastrointestinal tract of dogs, as well as the larvae of Dirofilaria immitis. The effect of milbemycin is expressed by increasing the permeability of cell membranes to chlorine ions, which leads to overpolarization of the membranes of nerve and muscle tissue cells, paralysis and death of the parasite. The maximum concentration of milbemycin oxime in the blood plasma of dogs is achieved within 1-2 hours. It is excreted from the body mainly unchanged, the half-life is about 1.5 days.

The drug begins to act 30 minutes after use.

One dose of the drug guarantees the destruction of fleas in 6 hours, ixodid ticks in 12 hours
Destruction of ixodid ticks within a month - in 8 hours
Fleas die before eggs are laid, which prevents the appearance of new parasites
Prevents re-infection within a month
The effectiveness of treatment of generalized demodicosis and sarcoptic mange in dogs is 99%

In terms of the degree of impact on the body, NexGard Spectra is a low-hazard substance (hazard class 4 according to GOST 12.1.007-76), in doses recommended by a doctor, it does not cause disruption of embryonic development or toxic effects on embryos, has no mutagenic properties, and does not have an irritating effect.
The drug is toxic to bees, as well as fish and other aquatic organisms. APPLICATION

Treatment of dog acarosis, which is caused by ticks and fleas, when infected with gastrointestinal nematodes, complex therapy of allergic dermatitis, prevention of dirofilariasis in dogs. To prevent dirofilariasis, the drug

NexGuard Spectra is used monthly in the spring-summer-autumn period, starting a month before the start of summer by the carriers of the pathogen - mosquitoes and mosquitoes, and ends no earlier than a month after the end of summer.

NexGard Spectra has a pleasant aroma and taste and, as a rule, is well eaten by dogs; otherwise, the drug is fed with food. It is necessary to make sure that the dog has completely swallowed the required dose of the drug. A contraindication for use is the increased individual sensitivity of the animal to the active substances (components) of the drug.

Do not use on sick or weakened animals. Do not use on puppies under 8 weeks of age and weighing up to 2 kg. Do not use on animals other than dogs. Breaking tablets is not allowed. NexgarD Spectra is intended for monthly use in dogs older than 8 weeks and weighing more than 2 kilograms. The tablets can be used with or without food.

NexgarD Spectra has no restrictions on bathing or washing with shampoo before and after using the drug. You can pet your dog immediately after using NexgarD Spectra.

Reviews

Artem, Belgorod

“Nexgard Spectra was recommended to me by a veterinarian. It is very convenient when one tablet protects my dog from fleas, ticks and worms. Now I weigh my Labrador every first day of the month and give him the right dosage.”

Valentina, Stavropol

“My Yorkshire Terrier has a beautiful harness with rhinestones and delicate pink clips. So I didn't want to put a flea collar on Molly. A friend advised me to give my dog Nexgard Spectra tablets, which also protect against parasites.”